Pseudomonas aeruginosa PA7, PSPA7_4841 (dnaE2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003676 nucleic acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01336
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02811
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07733
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003887 DNA-directed DNA polymerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01902
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008408 3'-5' exonuclease activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07733
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other PA7 genes in this class
Putative enzymes Other PA7 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF14579 Helix-hairpin-helix motif IPR029460 DNA polymerase, helix-hairpin-helix motif 766 855 8.3E-23
NCBIfam TIGR00594 JCVI: DNA polymerase III subunit alpha IPR004805 Error-prone DNA polymerase/DNA polymerase III subunit alpha DnaE/PolC 5 969 0.0
Gene3D G3DSA:1.10.150.870 - - - 755 843 5.8E-10
Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. IPR023073 DNA polymerase, error-prone 4 1024 13.939739
SUPERFAMILY SSF89550 PHP domain-like IPR016195 Polymerase/histidinol phosphatase-like 4 186 3.14E-11
Pfam PF02811 PHP domain IPR004013 PHP domain 6 122 9.3E-15
CDD cd04485 DnaE_OBF - - 935 1022 1.86743E-20
PANTHER PTHR32294 DNA POLYMERASE III SUBUNIT ALPHA IPR004805 Error-prone DNA polymerase/DNA polymerase III subunit alpha DnaE/PolC 1 1012 0.0
Pfam PF07733 Bacterial DNA polymerase III alpha NTPase domain IPR011708 Bacterial DNA polymerase III, alpha subunit, NTPase domain 268 522 1.1E-82
Gene3D G3DSA:3.20.20.140 - - - 1 245 1.9E-59
CDD cd07434 PHP_PolIIIA_DnaE2 - - 4 255 1.39374E-118
FunFam G3DSA:1.10.150.870:FF:000002 Error-prone DNA polymerase - - 751 843 4.8E-32
Pfam PF17657 Bacterial DNA polymerase III alpha subunit finger domain IPR040982 DNA polymerase III alpha subunit finger domain 525 692 2.4E-57
SMART SM00481 npolultra IPR003141 Polymerase/histidinol phosphatase, N-terminal 5 72 4.5E-11
Pfam PF01336 OB-fold nucleic acid binding domain IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type 934 1006 9.6E-8

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.