Pseudomonas aeruginosa PA7, PSPA7_6203 (glyA1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0019264 glycine biosynthetic process from serine
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0035999 tetrahydrofolate interconversion
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030170 pyridoxal phosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004372 glycine hydroxymethyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pap00630 Glyoxylate and dicarboxylate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap00680 Methane metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap00460 Cyanoamino acid metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap00670 One carbon pool by folate 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. IPR001085 Serine hydroxymethyltransferase 7 417 53.033344
Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase, domain 1 IPR015422 Pyridoxal phosphate-dependent transferase, small domain 11 416 0.0
SUPERFAMILY SSF53383 PLP-dependent transferases IPR015424 Pyridoxal phosphate-dependent transferase 7 416 0.0
PANTHER PTHR11680 SERINE HYDROXYMETHYLTRANSFERASE IPR001085 Serine hydroxymethyltransferase 7 388 0.0
Pfam PF00464 Serine hydroxymethyltransferase IPR039429 Serine hydroxymethyltransferase-like domain 11 386 0.0
FunFam G3DSA:3.40.640.10:FF:000001 Serine hydroxymethyltransferase - - 37 280 0.0
PIRSF PIRSF000412 SHMT IPR001085 Serine hydroxymethyltransferase 1 415 0.0
FunFam G3DSA:3.90.1150.10:FF:000003 Serine hydroxymethyltransferase - - 276 416 3.3E-59
Gene3D G3DSA:3.40.640.10 - IPR015421 Pyridoxal phosphate-dependent transferase, major domain 37 280 0.0
CDD cd00378 SHMT IPR001085 Serine hydroxymethyltransferase 11 409 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.