Pseudomonas aeruginosa PA7, PSPA7_6217 (aspA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF48557
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016829 lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF10415
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006099 tricarboxylic acid cycle
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF10415
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008797 aspartate ammonia-lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00839
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006531 aspartate metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00839
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PA7 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pap00250 Alanine, aspartate and glutamate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:1.10.40.30:FF:000002 Fumarate hydratase class II - - 413 468 1.1E-17
FunFam G3DSA:1.10.275.10:FF:000001 Fumarate hydratase, mitochondrial - - 8 143 1.3E-52
Pfam PF00206 Lyase IPR022761 Fumarate lyase, N-terminal 15 347 4.2E-98
FunFam G3DSA:1.20.200.10:FF:000001 Fumarate hydratase, mitochondrial - - 144 411 2.3E-112
Gene3D G3DSA:1.10.275.10 - IPR024083 Fumarase/histidase, N-terminal 8 143 5.8E-53
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 139 157 1.9E-28
CDD cd01357 Aspartase - - 8 459 0.0
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 276 303 1.9E-28
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 184 202 1.9E-28
Pfam PF10415 Fumarase C C-terminus IPR018951 Fumarase C, C-terminal 413 465 3.3E-20
SUPERFAMILY SSF48557 L-aspartase-like IPR008948 L-Aspartase-like 7 465 0.0
NCBIfam TIGR00839 JCVI: aspartate ammonia-lyase IPR004708 Aspartate ammonia-lyase 8 467 0.0
Gene3D G3DSA:1.20.200.10 Fumarase/aspartase (Central domain) - - 144 412 2.6E-80
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 322 338 1.9E-28
Gene3D G3DSA:1.10.40.30 - - - 413 468 1.5E-17
PANTHER PTHR42696 ASPARTATE AMMONIA-LYASE - - 7 470 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.