Pseudomonas aeruginosa M18, PAM18_0002 (dnaN)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR30478
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008408 3'-5' exonuclease activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02767
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR30478
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0009360 DNA polymerase III complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR30478
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003887 DNA-directed DNA polymerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02767
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other M18 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG paf00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf03440 Homologous recombination 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf03030 DNA replication 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf03430 Mismatch repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF55979 DNA clamp IPR046938 DNA clamp superfamily 1 120 3.14E-29
Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain IPR022634 DNA polymerase III, beta sliding clamp, N-terminal 1 119 8.9E-42
NCBIfam TIGR00663 JCVI: DNA polymerase III subunit beta IPR001001 DNA polymerase III, beta sliding clamp 1 367 2.5E-110
Gene3D G3DSA:3.10.150.10 DNA Polymerase III, subunit A, domain 2 - - 249 367 1.4E-34
Gene3D G3DSA:3.10.150.10 DNA Polymerase III, subunit A, domain 2 - - 1 123 6.2E-50
PANTHER PTHR30478 DNA POLYMERASE III SUBUNIT BETA IPR001001 DNA polymerase III, beta sliding clamp 1 367 0.0
Pfam PF02767 DNA polymerase III beta subunit, central domain IPR022637 DNA polymerase III, beta sliding clamp, central 130 244 1.8E-39
FunFam G3DSA:3.10.150.10:FF:000003 Beta sliding clamp - - 249 367 2.7E-59
Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain IPR022635 DNA polymerase III, beta sliding clamp, C-terminal 247 366 2.4E-40
FunFam G3DSA:3.10.150.10:FF:000002 Beta sliding clamp - - 124 248 2.0E-61
Gene3D G3DSA:3.10.150.10 DNA Polymerase III, subunit A, domain 2 - - 125 248 2.9E-41
SMART SM00480 pol35 IPR001001 DNA polymerase III, beta sliding clamp 17 363 0.0
SUPERFAMILY SSF55979 DNA clamp IPR046938 DNA clamp superfamily 246 367 7.25E-38
PIRSF PIRSF000804 DNA_pol_III_b IPR001001 DNA polymerase III, beta sliding clamp 1 367 2.9E-125
FunFam G3DSA:3.10.150.10:FF:000001 Beta sliding clamp - - 1 123 5.2E-55
SUPERFAMILY SSF55979 DNA clamp IPR046938 DNA clamp superfamily 126 245 3.14E-31
CDD cd00140 beta_clamp IPR001001 DNA polymerase III, beta sliding clamp 1 366 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.