Pseudomonas aeruginosa M18, PAM18_0053 (phzH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01536
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006529 asparagine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01536
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Putative enzymes Other M18 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG paf00250 Alanine, aspartate and glutamate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00712 AsnB IPR033738 Asparagine synthase, N-terminal domain 2 225 3.11864E-104
Gene3D G3DSA:3.60.20.10 Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 IPR029055 Nucleophile aminohydrolases, N-terminal 11 223 1.2E-60
NCBIfam TIGR01536 JCVI: asparagine synthase (glutamine-hydrolyzing) IPR006426 Asparagine synthase, glutamine-hydrolyzing 2 299 5.7E-107
SUPERFAMILY SSF56235 N-terminal nucleophile aminohydrolases (Ntn hydrolases) IPR029055 Nucleophile aminohydrolases, N-terminal 1 226 1.03E-62
Pfam PF13537 Glutamine amidotransferase domain IPR017932 Glutamine amidotransferase type 2 domain 48 170 1.1E-43
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 224 301 2.2E-13
Pfam PF00733 Asparagine synthase IPR001962 Asparagine synthase 242 296 7.2E-13
PANTHER PTHR43284 ASPARAGINE SYNTHETASE (GLUTAMINE-HYDROLYZING) - - 1 299 3.5E-100
SUPERFAMILY SSF52402 Adenine nucleotide alpha hydrolases-like - - 221 296 7.33E-13

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.