Pseudomonas aeruginosa M18, PAM18_0584

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009396 folic acid-containing compound biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01498
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003848 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01498
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other M18 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG paf00790 Folate biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR43071 2-AMINO-4-HYDROXY-6-HYDROXYMETHYLDIHYDROPTERIDINE PYROPHOSPHOKINASE - - 1 162 3.4E-34
CDD cd00483 HPPK IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK 6 128 2.27666E-41
Gene3D G3DSA:3.30.70.560 - IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily 5 172 2.9E-34
SUPERFAMILY SSF55083 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily 5 152 4.05E-38
Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK 7 130 3.4E-22
NCBIfam TIGR01498 JCVI: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK 6 130 6.5E-23

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.