Pseudomonas aeruginosa M18, PAM18_1807 (hisC2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0030170 pyridoxal phosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00155
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000105 histidine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01023
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004400 histidinol-phosphate transaminase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01023
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009058 biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00155
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other M18 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG paf01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf00400 Phenylalanine, tyrosine and tryptophan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf00350 Tyrosine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf00340 Histidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf00401 Novobiocin biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf00360 Phenylalanine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00609 AAT_like - - 51 376 2.24303E-61
SUPERFAMILY SSF53383 PLP-dependent transferases IPR015424 Pyridoxal phosphate-dependent transferase 29 378 1.95E-80
Gene3D G3DSA:3.40.640.10 - IPR015421 Pyridoxal phosphate-dependent transferase, major domain 62 286 3.2E-115
Pfam PF00155 Aminotransferase class I and II IPR004839 Aminotransferase, class I/classII 50 374 3.3E-49
PANTHER PTHR43643 HISTIDINOL-PHOSPHATE AMINOTRANSFERASE 2 - - 23 378 1.7E-103
Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase, domain 1 IPR015422 Pyridoxal phosphate-dependent transferase, small domain 41 374 3.2E-115
NCBIfam TIGR01141 JCVI: histidinol-phosphate transaminase IPR005861 Histidinol-phosphate aminotransferase family 22 376 1.1E-115
Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. IPR005861 Histidinol-phosphate aminotransferase family 19 378 62.765633

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.