Pseudomonas aeruginosa DK2, PADK2_02150
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Biological Process | GO:0055085 | transmembrane transport |
Inferred from Sequence Model
Term mapped from: InterPro:PF00873
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0015562 | efflux transmembrane transporter activity |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00915
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0042908 | xenobiotic transport |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00915
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0022857 | transmembrane transporter activity |
Inferred from Sequence Model
Term mapped from: InterPro:PF00873
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Cellular Component | GO:0016020 | membrane |
Inferred from Sequence Model
Term mapped from: InterPro:PF00873
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
|
|
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | pdk01501 | beta-Lactam resistance | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pdk01503 | Cationic antimicrobial peptide (CAMP) resistance | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Gene3D | G3DSA:1.20.1640.10 | Multidrug efflux transporter AcrB transmembrane domain | - | - | 271 | 456 | 0.0 |
| PANTHER | PTHR32063 | - | IPR001036 | Acriflavin resistance protein | 2 | 87 | 0.0 |
| SUPERFAMILY | SSF82693 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | - | - | 78 | 269 | 2.27E-24 |
| SUPERFAMILY | SSF82866 | Multidrug efflux transporter AcrB transmembrane domain | - | - | 235 | 436 | 9.68E-50 |
| PRINTS | PR00702 | Acriflavin resistance protein family signature | IPR001036 | Acriflavin resistance protein | 36 | 54 | 4.3E-39 |
| Gene3D | G3DSA:3.30.2090.10 | Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | IPR027463 | Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains | 665 | 753 | 0.0 |
| Gene3D | G3DSA:1.20.1640.10 | Multidrug efflux transporter AcrB transmembrane domain | - | - | 7 | 37 | 2.8E-24 |
| NCBIfam | TIGR00915 | JCVI: efflux RND transporter permease subunit | IPR004764 | Multidrug resistance protein MdtF-like | 84 | 983 | 0.0 |
| Gene3D | G3DSA:3.30.70.1440 | Multidrug efflux transporter AcrB pore domain | - | - | 613 | 811 | 0.0 |
| Gene3D | G3DSA:1.20.1640.10 | Multidrug efflux transporter AcrB transmembrane domain | - | - | 457 | 964 | 0.0 |
| SUPERFAMILY | SSF82866 | Multidrug efflux transporter AcrB transmembrane domain | - | - | 747 | 966 | 1.83E-46 |
| Pfam | PF00873 | AcrB/AcrD/AcrF family | IPR001036 | Acriflavin resistance protein | 83 | 966 | 0.0 |
| FunFam | G3DSA:3.30.2090.10:FF:000002 | Efflux pump membrane transporter | - | - | 665 | 753 | 9.8E-45 |
| SUPERFAMILY | SSF82714 | Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | IPR027463 | Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains | 121 | 210 | 9.94E-23 |
| Gene3D | G3DSA:3.30.2090.10 | Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | IPR027463 | Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains | 119 | 217 | 0.0 |
| Gene3D | G3DSA:3.30.70.1430 | Multidrug efflux transporter AcrB pore domain | - | - | 511 | 612 | 0.0 |
| FunFam | G3DSA:1.20.1640.10:FF:000002 | Efflux pump membrane transporter | - | - | 796 | 963 | 5.0E-81 |
| SUPERFAMILY | SSF82693 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | - | - | 506 | 610 | 1.2E-30 |
| FunFam | G3DSA:3.30.70.1430:FF:000002 | Efflux pump membrane transporter | - | - | 511 | 612 | 3.2E-39 |
| FunFam | G3DSA:3.30.2090.10:FF:000001 | Efflux pump membrane transporter | - | - | 119 | 217 | 1.3E-44 |
| PRINTS | PR00702 | Acriflavin resistance protein family signature | IPR001036 | Acriflavin resistance protein | 493 | 510 | 4.3E-39 |
| Gene3D | G3DSA:3.30.70.1430 | Multidrug efflux transporter AcrB pore domain | - | - | 38 | 87 | 2.8E-24 |
| PRINTS | PR00702 | Acriflavin resistance protein family signature | IPR001036 | Acriflavin resistance protein | 562 | 576 | 4.3E-39 |
| SUPERFAMILY | SSF82693 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | - | - | 38 | 88 | 1.05E-12 |
| SUPERFAMILY | SSF82714 | Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | IPR027463 | Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains | 663 | 750 | 8.5E-23 |
| Gene3D | G3DSA:3.30.70.1320 | Multidrug efflux transporter AcrB pore domain like | - | - | 88 | 270 | 0.0 |
| FunFam | G3DSA:1.20.1640.10:FF:000001 | Efflux pump membrane transporter | - | - | 260 | 450 | 6.8E-79 |
| PRINTS | PR00702 | Acriflavin resistance protein family signature | IPR001036 | Acriflavin resistance protein | 8 | 32 | 4.3E-39 |
| PRINTS | PR00702 | Acriflavin resistance protein family signature | IPR001036 | Acriflavin resistance protein | 417 | 440 | 4.3E-39 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.