Pseudomonas aeruginosa B136-33, G655_03210 (trpC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004425 indole-3-glycerol-phosphate synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00134_B
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other B136-33 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG psg00400 Phenylalanine, tyrosine and tryptophan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psg01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psg01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psg01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psg01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR22854 TRYPTOPHAN BIOSYNTHESIS PROTEIN IPR045186 Indole-3-glycerol phosphate synthase 5 265 3.5E-86
CDD cd00331 IGPS IPR013798 Indole-3-glycerol phosphate synthase domain 43 263 1.68165E-113
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 1 270 4.0E-106
Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. IPR013798 Indole-3-glycerol phosphate synthase domain 5 265 36.578224
FunFam G3DSA:3.20.20.70:FF:000024 Indole-3-glycerol phosphate synthase - - 1 267 1.4E-96
SUPERFAMILY SSF51366 Ribulose-phoshate binding barrel IPR011060 Ribulose-phosphate binding barrel 14 265 2.24E-86
Pfam PF00218 Indole-3-glycerol phosphate synthase IPR013798 Indole-3-glycerol phosphate synthase domain 7 263 4.3E-102

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.