Pseudomonas aeruginosa RP73, M062_05500

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009089 lysine biosynthetic process via diaminopimelate
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00950
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016829 lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR12128
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008840 4-hydroxy-tetrahydrodipicolinate synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00950
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other RP73 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG prp00300 Lysine biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG prp01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG prp01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG prp01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG prp01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG prp01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG prp00261 Monobactam biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00146 Dihydrodipicolinate synthase signature IPR002220 DapA-like 103 119 8.9E-35
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 1 291 9.8E-111
Coils Coil Coil - - 160 180 -
PANTHER PTHR12128 DIHYDRODIPICOLINATE SYNTHASE IPR002220 DapA-like 3 290 1.0E-81
SUPERFAMILY SSF51569 Aldolase - - 2 289 3.87E-107
Pfam PF00701 Dihydrodipicolinate synthetase family IPR002220 DapA-like 2 285 1.7E-109
Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA 1 287 69.373184
PRINTS PR00146 Dihydrodipicolinate synthase signature IPR002220 DapA-like 71 89 8.9E-35
NCBIfam TIGR00674 JCVI: 4-hydroxy-tetrahydrodipicolinate synthase IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA 5 286 3.3E-115
PRINTS PR00146 Dihydrodipicolinate synthase signature IPR002220 DapA-like 35 56 8.9E-35
CDD cd00950 DHDPS IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA 4 285 0.0
SMART SM01130 DHDPS_2 IPR002220 DapA-like 1 289 0.0
PIRSF PIRSF001365 DHDPS IPR002220 DapA-like 1 292 1.9E-100
PRINTS PR00146 Dihydrodipicolinate synthase signature IPR002220 DapA-like 128 145 8.9E-35

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.