Pseudomonas entomophila L48, PSEEN0031 (aroE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0019632 shikimate metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00507
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004764 shikimate 3-dehydrogenase (NADP+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF08501
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050661 NADP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00507
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pen01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pen01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pen00400 Phenylalanine, tyrosine and tryptophan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pen01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pen01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF18317 Shikimate 5'-dehydrogenase C-terminal domain IPR041121 SDH, C-terminal 245 275 5.1E-12
FunFam G3DSA:3.40.50.720:FF:000104 Shikimate dehydrogenase (NADP(+)) - - 108 252 5.9E-56
PANTHER PTHR21089 SHIKIMATE DEHYDROGENASE IPR022893 Shikimate dehydrogenase family 6 265 1.3E-60
Pfam PF01488 Shikimate / quinate 5-dehydrogenase IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase 123 198 8.3E-11
NCBIfam TIGR00507 JCVI: shikimate dehydrogenase IPR011342 Shikimate dehydrogenase 11 278 3.6E-80
SUPERFAMILY SSF53223 Aminoacid dehydrogenase-like, N-terminal domain IPR046346 Aminoacid dehydrogenase-like, N-terminal domain superfamily 8 107 1.61E-29
Gene3D G3DSA:3.40.50.10860 Leucine Dehydrogenase, chain A, domain 1 - - 13 262 1.1E-94
Gene3D G3DSA:3.40.50.720 - - - 108 252 1.1E-94
CDD cd01065 NAD_bind_Shikimate_DH - - 107 262 4.33774E-45
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 108 277 1.74E-40
Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. IPR022893 Shikimate dehydrogenase family 8 277 31.783333
FunFam G3DSA:3.40.50.10860:FF:000006 Shikimate dehydrogenase (NADP(+)) - - 12 127 3.0E-41
Pfam PF08501 Shikimate dehydrogenase substrate binding domain IPR013708 Shikimate dehydrogenase substrate binding, N-terminal 13 94 1.8E-24

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.