Pseudomonas stutzeri DSM 10701, PSJM300_01740

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005829 cytosol
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00676
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00676
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009086 methionine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00676
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006555 methionine metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02219
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG psj01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psj00670 One carbon pool by folate 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc folate transformations II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc folate transformations I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG psj01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psj01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR00676 JCVI: methylenetetrahydrofolate reductase [NAD(P)H] IPR004620 5,10-methylenetetrahydrofolate reductase 9 279 2.3E-100
PANTHER PTHR45754 METHYLENETETRAHYDROFOLATE REDUCTASE - - 4 281 7.9E-83
CDD cd00537 MTHFR IPR003171 Methylenetetrahydrofolate reductase-like 9 279 4.45443E-128
FunFam G3DSA:3.20.20.220:FF:000014 Methylenetetrahydrofolate reductase - - 2 282 0.0
Gene3D G3DSA:3.20.20.220 - - - 1 282 3.2E-93
SUPERFAMILY SSF51730 FAD-linked oxidoreductase IPR029041 FAD-linked oxidoreductase-like 3 281 1.28E-95
Pfam PF02219 Methylenetetrahydrofolate reductase IPR003171 Methylenetetrahydrofolate reductase-like 4 280 1.8E-89

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.