Pseudomonas stutzeri RCH2, Psest_0283

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004735 pyrroline-5-carboxylate reductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00112
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006561 proline biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00112
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG psh01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psh00330 Arginine and proline metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psh01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psh01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psh01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal 5 99 5.1E-21
Coils Coil Coil - - 258 274 -
PIRSF PIRSF000193 P5CR IPR000304 Pyrroline-5-carboxylate reductase 4 271 4.3E-81
FunFam G3DSA:1.10.3730.10:FF:000001 Pyrroline-5-carboxylate reductase - - 167 271 1.1E-33
NCBIfam TIGR00112 JCVI: pyrroline-5-carboxylate reductase IPR000304 Pyrroline-5-carboxylate reductase 6 268 1.3E-78
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 5 161 3.41E-36
SUPERFAMILY SSF48179 6-phosphogluconate dehydrogenase C-terminal domain-like IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily 163 271 3.06E-35
Gene3D G3DSA:1.10.3730.10 - - - 166 272 2.4E-38
Gene3D G3DSA:3.40.50.720 - - - 1 165 8.3E-52
FunFam G3DSA:3.40.50.720:FF:000105 Pyrroline-5-carboxylate reductase - - 1 165 5.8E-58
Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain 164 268 2.5E-36
PANTHER PTHR11645 PYRROLINE-5-CARBOXYLATE REDUCTASE - - 5 271 2.0E-70
Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. IPR000304 Pyrroline-5-carboxylate reductase 4 268 27.228748

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.