Pseudomonas mendocina NK-01, MDS_4451

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0035999 tetrahydrofolate interconversion
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004372 glycine hydroxymethyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030170 pyridoxal phosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019264 glycine biosynthetic process from serine
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pmk01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pmk01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pmk01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pmk01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pmk00630 Glyoxylate and dicarboxylate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pmk01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pmk00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pmk00670 One carbon pool by folate 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pmk00680 Methane metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pmk01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pmk00460 Cyanoamino acid metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. IPR001085 Serine hydroxymethyltransferase 7 417 52.955914
FunFam G3DSA:3.40.640.10:FF:000001 Serine hydroxymethyltransferase - - 37 280 0.0
FunFam G3DSA:3.90.1150.10:FF:000003 Serine hydroxymethyltransferase - - 275 416 2.3E-59
PANTHER PTHR11680 SERINE HYDROXYMETHYLTRANSFERASE IPR001085 Serine hydroxymethyltransferase 7 388 0.0
PIRSF PIRSF000412 SHMT IPR001085 Serine hydroxymethyltransferase 1 413 0.0
Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase, domain 1 IPR015422 Pyridoxal phosphate-dependent transferase, small domain 11 413 0.0
Pfam PF00464 Serine hydroxymethyltransferase IPR039429 Serine hydroxymethyltransferase-like domain 10 386 0.0
CDD cd00378 SHMT IPR001085 Serine hydroxymethyltransferase 11 409 0.0
Gene3D G3DSA:3.40.640.10 - IPR015421 Pyridoxal phosphate-dependent transferase, major domain 37 289 0.0
SUPERFAMILY SSF53383 PLP-dependent transferases IPR015424 Pyridoxal phosphate-dependent transferase 5 416 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.