Pseudomonas savastanoi pv. phaseolicola 1448A, PSPPH_0625 (folK1)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0003848 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01498
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0009396 | folic acid-containing compound biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01498
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
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Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| MetaCyc | 6-hydroxymethyl-dihydropterin diphosphate biosynthesis V (<i>Pyrococcus</i>) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | 6-hydroxymethyl-dihydropterin diphosphate biosynthesis II (<i>Methanocaldococcus</i>) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | 6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | psp01100 | Metabolic pathways | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | tetrahydromethanopterin biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | 6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | psp00790 | Folate biosynthesis | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Gene3D | G3DSA:3.30.70.560 | - | IPR035907 | 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily | 1 | 153 | 4.8E-29 |
| Pfam | PF01288 | 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) | IPR000550 | 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK | 7 | 130 | 4.1E-19 |
| CDD | cd00483 | HPPK | IPR000550 | 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK | 6 | 128 | 3.41674E-39 |
| PANTHER | PTHR43071 | 2-AMINO-4-HYDROXY-6-HYDROXYMETHYLDIHYDROPTERIDINE PYROPHOSPHOKINASE | - | - | 1 | 151 | 9.3E-28 |
| NCBIfam | TIGR01498 | JCVI: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase | IPR000550 | 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK | 7 | 130 | 3.3E-19 |
| SUPERFAMILY | SSF55083 | 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | IPR035907 | 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily | 4 | 154 | 6.41E-35 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.