Pseudomonas sp. UW4, PputUW4_03386 (pheS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000049 tRNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01409
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006432 phenylalanyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02912
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02912
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02912
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0043039 tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01409
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004826 phenylalanine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00281
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01409
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02912
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG ppuu00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial 8 337 50.935478
CDD cd00496 PheRS_alpha_core - - 107 332 1.97291E-126
Pfam PF01409 tRNA synthetases class II core domain (F) IPR002319 Phenylalanyl-tRNA synthetase 92 337 2.0E-108
Gene3D G3DSA:3.30.930.10 Bira Bifunctional Protein; Domain 2 IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) 7 338 0.0
PANTHER PTHR11538 PHENYLALANYL-TRNA SYNTHETASE - - 96 337 7.7E-31
SUPERFAMILY SSF46589 tRNA-binding arm IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm 13 99 4.87E-23
FunFam G3DSA:3.30.930.10:FF:000003 Phenylalanine--tRNA ligase alpha subunit - - 8 338 0.0
Coils Coil Coil - - 1 21 -
Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal 20 87 1.2E-25
SUPERFAMILY SSF55681 Class II aaRS and biotin synthetases IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) 92 338 8.71E-82
NCBIfam TIGR00468 JCVI: phenylalanine--tRNA ligase subunit alpha IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit 38 337 4.1E-108

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.