Pseudomonas sp. UW4, PputUW4_04721 (aroE2)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0004764	shikimate 3-dehydrogenase (NADP+) activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR21089	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	ppuu01230	Biosynthesis of amino acids	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	ppuu01130	Biosynthesis of antibiotics	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	ppuu00400	Phenylalanine, tyrosine and tryptophan biosynthesis	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	ppuu01110	Biosynthesis of secondary metabolites	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
MetaCyc		chorismate biosynthesis from 3-dehydroquinate	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG	ppuu01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Pfam	PF08501	Shikimate dehydrogenase substrate binding domain	IPR013708	Shikimate dehydrogenase substrate binding, N-terminal	11	98	9.7E-21
Gene3D	G3DSA:3.40.50.720	-	-	-	111	251	5.9E-76
Pfam	PF18317	Shikimate 5'-dehydrogenase C-terminal domain	IPR041121	SDH, C-terminal	251	277	3.7E-6
Gene3D	G3DSA:3.40.50.10860	Leucine Dehydrogenase, chain A, domain 1	-	-	11	270	5.9E-76
FunFam	G3DSA:3.40.50.720:FF:000086	Quinate/shikimate dehydrogenase	-	-	111	251	6.7E-41
Hamap	MF_00222	Shikimate dehydrogenase (NADP(+)) [aroE].	IPR022893	Shikimate dehydrogenase family	6	277	26.998362
SUPERFAMILY	SSF51735	NAD(P)-binding Rossmann-fold domains	IPR036291	NAD(P)-binding domain superfamily	111	280	3.63E-37
PANTHER	PTHR21089	SHIKIMATE DEHYDROGENASE	IPR022893	Shikimate dehydrogenase family	8	273	5.7E-57
CDD	cd01065	NAD_bind_Shikimate_DH	-	-	110	267	1.61366E-40
SUPERFAMILY	SSF53223	Aminoacid dehydrogenase-like, N-terminal domain	IPR046346	Aminoacid dehydrogenase-like, N-terminal domain superfamily	5	110	6.33E-27

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.