Pseudomonas sp. UW4, PputUW4_04946 (folK2)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Biological Process | GO:0009396 | folic acid-containing compound biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:PF01288
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0003848 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PF01288
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
|
|
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | ppuu00790 | Folate biosynthesis | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | ppuu01100 | Metabolic pathways | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| NCBIfam | TIGR01498 | JCVI: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase | IPR000550 | 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK | 6 | 130 | 9.8E-21 |
| Pfam | PF01288 | 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) | IPR000550 | 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK | 7 | 130 | 4.0E-20 |
| Gene3D | G3DSA:3.30.70.560 | - | IPR035907 | 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily | 1 | 153 | 1.6E-31 |
| SUPERFAMILY | SSF55083 | 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | IPR035907 | 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily | 4 | 152 | 9.68E-37 |
| PANTHER | PTHR43071 | 2-AMINO-4-HYDROXY-6-HYDROXYMETHYLDIHYDROPTERIDINE PYROPHOSPHOKINASE | - | - | 1 | 150 | 4.7E-30 |
| CDD | cd00483 | HPPK | IPR000550 | 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK | 6 | 128 | 2.99858E-40 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.