Pseudomonas sp. UW4, PputUW4_05373 (aspA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008797 aspartate ammonia-lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00839
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006099 tricarboxylic acid cycle
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF10415
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006531 aspartate metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00839
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF48557
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016829 lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF10415
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc TCA cycle VII (acetate-producers) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc TCA cycle II (plants and fungi) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc superpathway of glyoxylate cycle and fatty acid degradation InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc reductive TCA cycle II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc partial TCA cycle (obligate autotrophs) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG ppuu00250 Alanine, aspartate and glutamate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc methylaspartate cycle InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG ppuu01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc anaerobic energy metabolism (invertebrates, mitochondrial) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF10415 Fumarase C C-terminus IPR018951 Fumarase C, C-terminal 417 469 1.0E-19
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 188 206 1.4E-28
Pfam PF00206 Lyase IPR022761 Fumarate lyase, N-terminal 19 351 5.1E-99
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 280 307 1.4E-28
SUPERFAMILY SSF48557 L-aspartase-like IPR008948 L-Aspartase-like 11 469 0.0
Gene3D G3DSA:1.20.200.10 Fumarase/aspartase (Central domain) - - 148 416 3.9E-81
PANTHER PTHR42696 ASPARTATE AMMONIA-LYASE - - 10 474 0.0
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 143 161 1.4E-28
FunFam G3DSA:1.10.40.30:FF:000002 Fumarate hydratase class II - - 417 472 4.8E-17
FunFam G3DSA:1.20.200.10:FF:000001 Fumarate hydratase, mitochondrial - - 148 415 7.0E-114
Gene3D G3DSA:1.10.275.10 - IPR024083 Fumarase/histidase, N-terminal 12 147 4.9E-52
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 326 342 1.4E-28
CDD cd01357 Aspartase - - 12 463 0.0
FunFam G3DSA:1.10.275.10:FF:000001 Fumarate hydratase, mitochondrial - - 12 147 2.9E-52
NCBIfam TIGR00839 JCVI: aspartate ammonia-lyase IPR004708 Aspartate ammonia-lyase 12 472 0.0
Gene3D G3DSA:1.10.40.30 - - - 417 472 4.5E-17

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.