Pseudomonas protegens Pf-5, PFL_0409 (hutI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:2.30.40.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00372
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016787 hydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01979
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00372
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019556 histidine catabolic process to glutamate and formamide
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00372
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc L-histidine degradation II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pfl01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfl00340 Histidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc L-histidine degradation III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:2.30.40.10 Urease, subunit C, domain 1 IPR011059 Metal-dependent hydrolase, composite domain superfamily 10 393 0.0
Pfam PF01979 Amidohydrolase family IPR006680 Amidohydrolase-related 57 380 2.1E-21
SUPERFAMILY SSF51338 Composite domain of metallo-dependent hydrolases IPR011059 Metal-dependent hydrolase, composite domain superfamily 1 397 6.0E-27
CDD cd01296 Imidazolone-5PH IPR005920 Imidazolonepropionase 33 396 0.0
FunFam G3DSA:3.20.20.140:FF:000007 Imidazolonepropionase - - 61 359 1.1E-122
SUPERFAMILY SSF51556 Metallo-dependent hydrolases IPR032466 Metal-dependent hydrolase 60 360 1.64E-87
PANTHER PTHR42752 IMIDAZOLONEPROPIONASE IPR005920 Imidazolonepropionase 15 397 0.0
Gene3D G3DSA:3.20.20.140 - - - 61 359 0.0
NCBIfam TIGR01224 JCVI: imidazolonepropionase IPR005920 Imidazolonepropionase 21 396 0.0
Hamap MF_00372 Imidazolonepropionase [hutI]. IPR005920 Imidazolonepropionase 2 399 42.887894

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.