Pseudomonas protegens Pf-5, PFL_5839 (proC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006561 proline biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00112
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004735 pyrroline-5-carboxylate reductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00112
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pfl01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfl01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfl00330 Arginine and proline metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfl01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfl01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain 162 266 1.4E-35
SUPERFAMILY SSF48179 6-phosphogluconate dehydrogenase C-terminal domain-like IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily 161 269 1.28E-33
Gene3D G3DSA:1.10.3730.10 - - - 164 270 2.1E-37
NCBIfam TIGR00112 JCVI: pyrroline-5-carboxylate reductase IPR000304 Pyrroline-5-carboxylate reductase 6 266 2.9E-78
FunFam G3DSA:3.40.50.720:FF:000105 Pyrroline-5-carboxylate reductase - - 1 163 2.4E-57
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 5 159 4.13E-38
PANTHER PTHR11645 PYRROLINE-5-CARBOXYLATE REDUCTASE - - 3 269 1.0E-72
Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal 5 99 7.4E-23
FunFam G3DSA:1.10.3730.10:FF:000001 Pyrroline-5-carboxylate reductase - - 165 269 5.9E-32
Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. IPR000304 Pyrroline-5-carboxylate reductase 4 266 27.396706
Gene3D G3DSA:3.40.50.720 - - - 1 163 6.7E-55
PIRSF PIRSF000193 P5CR IPR000304 Pyrroline-5-carboxylate reductase 3 269 2.4E-81

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.