Pseudomonas protegens CHA0, PFLCHA0_c04160 (hutI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01296
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016787 hydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01979
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019556 histidine catabolic process to glutamate and formamide
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01296
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01296
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF51338
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pprc01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pprc00340 Histidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc L-histidine degradation III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc L-histidine degradation II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_00372 Imidazolonepropionase [hutI]. IPR005920 Imidazolonepropionase 1 374 39.760857
Gene3D G3DSA:3.20.20.140 - - - 36 334 0.0
CDD cd01296 Imidazolone-5PH IPR005920 Imidazolonepropionase 8 371 0.0
SUPERFAMILY SSF51556 Metallo-dependent hydrolases IPR032466 Metal-dependent hydrolase 35 335 3.53E-88
SUPERFAMILY SSF51338 Composite domain of metallo-dependent hydrolases IPR011059 Metal-dependent hydrolase, composite domain superfamily 2 372 3.36E-19
Pfam PF01979 Amidohydrolase family IPR006680 Amidohydrolase-related 32 355 1.1E-21
FunFam G3DSA:3.20.20.140:FF:000007 Imidazolonepropionase - - 36 334 6.4E-123
PANTHER PTHR42752 IMIDAZOLONEPROPIONASE IPR005920 Imidazolonepropionase 3 372 0.0
Gene3D G3DSA:2.30.40.10 Urease, subunit C, domain 1 IPR011059 Metal-dependent hydrolase, composite domain superfamily 4 368 0.0
NCBIfam TIGR01224 JCVI: imidazolonepropionase IPR005920 Imidazolonepropionase 5 371 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.