Pseudomonas protegens CHA0, PFLCHA0_c60860 (purK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004638 phosphoribosylaminoimidazole carboxylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01161
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006189 'de novo' IMP biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01161
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.30.1490.20
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pprc01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pprc00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pprc01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pprc01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.30.1490.20 - IPR013815 ATP-grasp fold, subdomain 1 102 175 6.0E-26
FunFam G3DSA:3.30.470.20:FF:000029 N5-carboxyaminoimidazole ribonucleotide synthase - - 176 359 1.2E-71
SUPERFAMILY SSF56059 Glutathione synthetase ATP-binding domain-like - - 97 292 7.25E-57
SUPERFAMILY SSF52440 PreATP-grasp domain IPR016185 Pre-ATP-grasp domain superfamily 2 94 7.63E-23
FunFam G3DSA:3.30.1490.20:FF:000015 N5-carboxyaminoimidazole ribonucleotide synthase - - 102 175 1.1E-31
Pfam PF17769 Phosphoribosylaminoimidazole carboxylase C-terminal domain IPR040686 Phosphoribosylaminoimidazole carboxylase, C-terminal domain 298 349 1.2E-12
Gene3D G3DSA:3.30.470.20 - - - 176 360 8.9E-62
Pfam PF02222 ATP-grasp domain IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type 106 272 2.1E-57
NCBIfam TIGR01161 JCVI: 5-(carboxyamino)imidazole ribonucleotide synthase IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit 2 348 3.8E-109
PANTHER PTHR11609 PURINE BIOSYNTHESIS PROTEIN 6/7, PUR6/7 - - 2 354 8.3E-108
Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit 2 344 39.269676
SUPERFAMILY SSF51246 Rudiment single hybrid motif IPR011054 Rudiment single hybrid motif 297 357 1.8E-13
FunFam G3DSA:3.40.50.20:FF:000016 N5-carboxyaminoimidazole ribonucleotide synthase - - 1 101 8.2E-48
Gene3D G3DSA:3.40.50.20 - - - 1 101 1.2E-32

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.