Pseudomonas poae RE_1-1-14, H045_10880 (dnaE2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR32294
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003676 nucleic acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01336
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003887 DNA-directed DNA polymerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01902
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02811
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008408 3'-5' exonuclease activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR32294
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM00481 npolultra IPR003141 Polymerase/histidinol phosphatase, N-terminal 4 71 4.9E-10
Pfam PF07733 Bacterial DNA polymerase III alpha NTPase domain IPR011708 Bacterial DNA polymerase III, alpha subunit, NTPase domain 268 522 7.1E-80
Gene3D G3DSA:1.10.150.870 - - - 754 842 1.7E-7
CDD cd04485 DnaE_OBF - - 935 1013 1.62789E-20
Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. IPR023073 DNA polymerase, error-prone 3 1023 13.68759
SUPERFAMILY SSF89550 PHP domain-like IPR016195 Polymerase/histidinol phosphatase-like 3 184 4.12E-11
Pfam PF01336 OB-fold nucleic acid binding domain IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type 933 993 1.8E-6
NCBIfam TIGR00594 JCVI: DNA polymerase III subunit alpha IPR004805 Error-prone DNA polymerase/DNA polymerase III subunit alpha DnaE/PolC 4 968 0.0
CDD cd07434 PHP_PolIIIA_DnaE2 - - 3 255 5.76614E-122
Pfam PF02811 PHP domain IPR004013 PHP domain 5 126 4.2E-15
Pfam PF17657 Bacterial DNA polymerase III alpha subunit finger domain IPR040982 DNA polymerase III alpha subunit finger domain 525 691 4.8E-62
PANTHER PTHR32294 DNA POLYMERASE III SUBUNIT ALPHA IPR004805 Error-prone DNA polymerase/DNA polymerase III subunit alpha DnaE/PolC 1 1011 0.0
Gene3D G3DSA:3.20.20.140 - - - 1 245 1.9E-58
Pfam PF14579 Helix-hairpin-helix motif IPR029460 DNA polymerase, helix-hairpin-helix motif 765 854 1.2E-19

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.