Pseudomonas aeruginosa LESB58, PALES_38551 (ilvA2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009097 isoleucine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01124
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004794 L-threonine ammonia-lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01124
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other LESB58 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Glycine, serine and threonine metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00291 Pyridoxal-phosphate dependent enzyme IPR001926 Tryptophan synthase beta chain-like, PALP domain 30 317 1.1E-81
FunFam G3DSA:3.40.1020.10:FF:000001 L-threonine dehydratase - - 339 515 9.0E-75
NCBIfam TIGR01124 JCVI: threonine ammonia-lyase, biosynthetic IPR005787 Threonine dehydratase, biosynthetic 16 513 0.0
FunFam G3DSA:3.40.50.1100:FF:000008 L-threonine dehydratase - - 141 311 6.1E-70
SUPERFAMILY SSF53686 Tryptophan synthase beta subunit-like PLP-dependent enzymes IPR036052 Tryptophan synthase beta chain-like, PALP domain superfamily 16 366 1.7E-103
Gene3D G3DSA:3.40.50.1100 - IPR036052 Tryptophan synthase beta chain-like, PALP domain superfamily 65 156 2.9E-111
CDD cd01562 Thr-dehyd - - 17 321 0.0
Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase IPR001721 Threonine dehydratase, ACT-like domain 430 513 1.3E-25
PANTHER PTHR48078 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED - - 24 513 0.0
Gene3D G3DSA:3.40.1020.10 Biosynthetic Threonine Deaminase; Domain 3 IPR038110 Threonine dehydratase, ACT-like domain superfamily 339 514 1.2E-71
SUPERFAMILY SSF55021 ACT-like IPR045865 ACT-like domain 421 513 2.75E-27
Gene3D G3DSA:3.40.50.1100 - IPR036052 Tryptophan synthase beta chain-like, PALP domain superfamily 32 311 2.9E-111
CDD cd04906 ACT_ThrD-I_1 - - 339 423 1.79659E-40
CDD cd04907 ACT_ThrD-I_2 - - 434 513 2.46795E-44
Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase IPR001721 Threonine dehydratase, ACT-like domain 330 420 2.8E-22

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.