Pseudomonas aeruginosa LESB58, PALES_40391 (cobB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0042242 cobyrinic acid a,c-diamide synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00379
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07685
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other LESB58 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Cobalamin biosynthesis ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR00379 JCVI: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing) IPR004484 Cobyrinic acid a,c-diamide synthase CbiA 10 430 2.5E-82
Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain IPR011698 CobB/CobQ-like glutamine amidotransferase 239 418 1.4E-30
SUPERFAMILY SSF52317 Class I glutamine amidotransferase-like IPR029062 Class I glutamine amidotransferase-like 235 428 1.36E-31
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 8 194 1.77E-40
CDD cd05388 CobB_N - - 7 191 1.61902E-84
Gene3D G3DSA:3.40.50.880 - IPR029062 Class I glutamine amidotransferase-like 236 414 8.5E-11
CDD cd03130 GATase1_CobB - - 240 421 5.8306E-73
Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. IPR004484 Cobyrinic acid a,c-diamide synthase CbiA 6 421 39.260288
PANTHER PTHR43873 COBYRINATE A,C-DIAMIDE SYNTHASE IPR004484 Cobyrinic acid a,c-diamide synthase CbiA 7 432 5.4E-124
Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain 9 187 1.2E-12
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 45 182 1.7E-10

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.