Pseudomonas aeruginosa LESB58, PALES_46601 (dnaE2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008408 3'-5' exonuclease activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07733
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003887 DNA-directed DNA polymerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01902
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02811
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07733
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Putative enzymes Other LESB58 genes in this class
DNA replication, recombination, modification and repair Other LESB58 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF14579 Helix-hairpin-helix motif IPR029460 DNA polymerase, helix-hairpin-helix motif 774 862 1.2E-21
Pfam PF17657 Bacterial DNA polymerase III alpha subunit finger domain IPR040982 DNA polymerase III alpha subunit finger domain 532 698 5.9E-58
Gene3D G3DSA:1.10.150.870 - - - 762 850 1.8E-8
Gene3D G3DSA:3.20.20.140 - - - 5 252 4.4E-64
NCBIfam TIGR00594 JCVI: DNA polymerase III subunit alpha IPR004805 Error-prone DNA polymerase/DNA polymerase III subunit alpha DnaE/PolC 12 975 0.0
Pfam PF07733 Bacterial DNA polymerase III alpha NTPase domain IPR011708 Bacterial DNA polymerase III, alpha subunit, NTPase domain 275 529 6.5E-83
SMART SM00481 npolultra IPR003141 Polymerase/histidinol phosphatase, N-terminal 12 79 1.0E-10
PANTHER PTHR32294 DNA POLYMERASE III SUBUNIT ALPHA IPR004805 Error-prone DNA polymerase/DNA polymerase III subunit alpha DnaE/PolC 8 1019 0.0
SUPERFAMILY SSF89550 PHP domain-like IPR016195 Polymerase/histidinol phosphatase-like 11 192 1.37E-10
CDD cd07434 PHP_PolIIIA_DnaE2 - - 11 262 8.06489E-129
FunFam G3DSA:1.10.150.870:FF:000002 Error-prone DNA polymerase - - 758 850 9.3E-30
Pfam PF02811 PHP domain IPR004013 PHP domain 13 130 4.8E-16
Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. IPR023073 DNA polymerase, error-prone 11 1031 14.017231
CDD cd04485 DnaE_OBF - - 942 1029 3.541E-18

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.