Pseudomonas aeruginosa LESB58, PALES_58201 (purK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004638 phosphoribosylaminoimidazole carboxylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01928
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006189 'de novo' IMP biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01928
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.30.1490.20
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other LESB58 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Purine metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.30.470.20 - - - 176 360 3.5E-62
FunFam G3DSA:3.30.470.20:FF:000029 N5-carboxyaminoimidazole ribonucleotide synthase - - 176 359 1.4E-71
PANTHER PTHR11609 PURINE BIOSYNTHESIS PROTEIN 6/7, PUR6/7 - - 2 357 1.3E-109
Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit 2 344 39.176777
SUPERFAMILY SSF52440 PreATP-grasp domain IPR016185 Pre-ATP-grasp domain superfamily 2 94 2.45E-22
Pfam PF17769 Phosphoribosylaminoimidazole carboxylase C-terminal domain IPR040686 Phosphoribosylaminoimidazole carboxylase, C-terminal domain 298 349 1.7E-12
SUPERFAMILY SSF56059 Glutathione synthetase ATP-binding domain-like - - 97 292 2.47E-56
NCBIfam TIGR01161 JCVI: 5-(carboxyamino)imidazole ribonucleotide synthase IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit 2 348 4.2E-108
Gene3D G3DSA:3.30.1490.20 - IPR013815 ATP-grasp fold, subdomain 1 102 175 2.6E-26
Pfam PF02222 ATP-grasp domain IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type 106 272 1.0E-57
FunFam G3DSA:3.40.50.20:FF:000016 N5-carboxyaminoimidazole ribonucleotide synthase - - 1 101 3.8E-48
FunFam G3DSA:3.30.1490.20:FF:000015 N5-carboxyaminoimidazole ribonucleotide synthase - - 102 175 1.7E-31
SUPERFAMILY SSF51246 Rudiment single hybrid motif IPR011054 Rudiment single hybrid motif 297 356 2.35E-13
Gene3D G3DSA:3.40.50.20 - - - 1 101 7.7E-33

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.