Pseudomonas aeruginosa 2192, PA2G_04346

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005829 cytosol
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00676
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006555 methionine metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02219
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009086 methionine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00676
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02219
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Central intermediary metabolism Other 2192 genes in this class
Amino acid biosynthesis and metabolism Other 2192 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51730 FAD-linked oxidoreductase IPR029041 FAD-linked oxidoreductase-like 8 288 1.16E-95
CDD cd00537 MTHFR IPR003171 Methylenetetrahydrofolate reductase-like 16 286 1.00627E-125
Pfam PF02219 Methylenetetrahydrofolate reductase IPR003171 Methylenetetrahydrofolate reductase-like 10 286 2.3E-88
PANTHER PTHR45754 METHYLENETETRAHYDROFOLATE REDUCTASE - - 9 288 1.2E-81
NCBIfam TIGR00676 JCVI: methylenetetrahydrofolate reductase [NAD(P)H] IPR004620 5,10-methylenetetrahydrofolate reductase 16 287 6.1E-100
Gene3D G3DSA:3.20.20.220 - - - 5 289 2.2E-92
FunFam G3DSA:3.20.20.220:FF:000014 Methylenetetrahydrofolate reductase - - 9 289 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.