Pseudomonas aeruginosa PACS2, A0K_RS00180 (trpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0000162 tryptophan biosynthetic process
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA0035
ECO:0000249
sequence similarity evidence used in automatic assertion
3127651
Molecular Function GO:0004834 tryptophan synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00290
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006568 tryptophan metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00290
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PACS2 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 1 268 1.9E-104
FunFam G3DSA:3.20.20.70:FF:000037 Tryptophan synthase alpha chain - - 1 266 4.4E-101
SUPERFAMILY SSF51366 Ribulose-phoshate binding barrel IPR011060 Ribulose-phosphate binding barrel 1 248 1.22E-92
Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. IPR002028 Tryptophan synthase, alpha chain 14 263 38.119148
PANTHER PTHR43406 TRYPTOPHAN SYNTHASE, ALPHA CHAIN IPR002028 Tryptophan synthase, alpha chain 3 262 1.1E-84
CDD cd04724 Tryptophan_synthase_alpha IPR002028 Tryptophan synthase, alpha chain 18 260 5.00303E-122
Pfam PF00290 Tryptophan synthase alpha chain IPR002028 Tryptophan synthase, alpha chain 8 263 6.5E-106
NCBIfam TIGR00262 JCVI: tryptophan synthase subunit alpha IPR002028 Tryptophan synthase, alpha chain 8 259 7.3E-81

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.