Pseudomonas aeruginosa PACS2, A0K_RS02000

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004735 pyrroline-5-carboxylate reductase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA0393
 ECO:0000249
sequence similarity evidence used in automatic assertion		 8479442
Biological Process GO:0006561 proline biosynthetic process
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA0393
 ECO:0000249
sequence similarity evidence used in automatic assertion		 8479442
Biological Process GO:0006561 proline biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01925
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004735 pyrroline-5-carboxylate reductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01925
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PACS2 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. IPR000304 Pyrroline-5-carboxylate reductase 4 267 27.870037
FunFam G3DSA:3.40.50.720:FF:000105 Pyrroline-5-carboxylate reductase - - 1 164 3.7E-60
SUPERFAMILY SSF48179 6-phosphogluconate dehydrogenase C-terminal domain-like IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily 162 270 1.87E-35
Gene3D G3DSA:1.10.3730.10 - - - 165 271 1.8E-40
FunFam G3DSA:1.10.3730.10:FF:000001 Pyrroline-5-carboxylate reductase - - 166 270 5.4E-35
NCBIfam TIGR00112 JCVI: pyrroline-5-carboxylate reductase IPR000304 Pyrroline-5-carboxylate reductase 6 267 6.9E-80
PIRSF PIRSF000193 P5CR IPR000304 Pyrroline-5-carboxylate reductase 3 270 2.7E-83
Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain 163 267 5.2E-38
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 5 160 8.86E-40
Gene3D G3DSA:3.40.50.720 - - - 3 164 7.7E-54
PANTHER PTHR11645 PYRROLINE-5-CARBOXYLATE REDUCTASE - - 5 270 2.9E-73
Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal 5 99 3.8E-23

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.