Pseudomonas aeruginosa PACS2, A0K_RS07555

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00672
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF47384
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF47384
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other PACS2 genes in this class
Transport of small molecules Other PACS2 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 393 403 1.1E-6
Pfam PF16750 Sensor domain of 2-component histidine kinase IPR031930 Two-component histidine kinase, sensor domain 40 149 1.9E-35
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 338 446 2.5E-25
Coils Coil Coil - - 267 287 -
Gene3D G3DSA:1.10.287.130 - - - 234 292 1.7E-6
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 375 389 1.1E-6
SMART SM00388 HisKA_10 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 234 293 7.6E-11
SUPERFAMILY SSF158472 HAMP domain-like - - 178 230 4.58E-7
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 232 288 4.88604E-8
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 235 292 2.6E-9
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 218 292 2.94E-11
SMART SM00304 HAMP_11 IPR003660 HAMP domain 178 233 4.1E-10
Gene3D G3DSA:3.30.450.170 - IPR038428 Two-component histidine kinase, sensor domain superfamily 27 150 3.9E-35
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 283 444 1.57E-31
CDD cd06225 HAMP - - 183 228 9.7412E-9
Gene3D G3DSA:6.10.340.10 - - - 155 233 1.0E-12
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 321 446 3.2E-28
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 408 426 1.1E-6
Pfam PF00672 HAMP domain IPR003660 HAMP domain 175 229 1.8E-12
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 341 432 3.3E-14
PANTHER PTHR45436 SENSOR HISTIDINE KINASE YKOH - - 4 446 1.3E-50

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.