Pseudomonas aeruginosa PACS2, A0K_RS29500

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:1901053 sarcosine catabolic process
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA5418
 ECO:0000249
sequence similarity evidence used in automatic assertion		 17951379
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07992
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0046653 tetrahydrofolate metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01372
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005515 protein binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.30.1360.120
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008115 sarcosine oxidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01372
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other PACS2 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc creatinine degradation II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc glycine betaine degradation I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature - - 459 477 1.5E-9
FunFam G3DSA:3.30.1360.120:FF:000038 Sarcosine oxidase subunit alpha - - 614 1004 0.0
PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature - - 172 194 1.5E-9
SUPERFAMILY SSF51905 FAD/NAD(P)-binding domain IPR036188 FAD/NAD(P)-binding domain superfamily 167 448 2.36E-33
PANTHER PTHR43104 L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL - - 1 948 1.3E-72
Gene3D G3DSA:3.30.1360.120 Probable tRNA modification gtpase trme; domain 1 IPR027266 GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 614 1004 3.2E-129
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature - - 173 192 3.4E-8
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature - - 283 301 3.4E-8
Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain - - 17 102 3.0E-22
FunFam G3DSA:3.50.50.60:FF:000476 Sarcosine oxidase subunit alpha - - 167 317 7.3E-101
Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase IPR023753 FAD/NAD(P)-binding domain 172 434 2.1E-12
Pfam PF17806 Sarcosine oxidase A3 domain IPR041117 SoxA, A3 domain 521 604 1.2E-31
Gene3D G3DSA:1.10.10.1100 - IPR041854 BFD-like [2Fe-2S]-binding domain superfamily 527 585 2.6E-6
Gene3D G3DSA:3.50.50.60 - IPR036188 FAD/NAD(P)-binding domain superfamily 167 317 2.7E-21
Pfam PF01571 Aminomethyltransferase folate-binding domain IPR006222 Aminomethyltransferase, folate-binding domain 619 884 1.4E-74
PIRSF PIRSF037980 Sarcos_oxid_alpha IPR006277 Sarcosine oxidase, alpha subunit 1 1004 0.0
SUPERFAMILY SSF103025 Folate-binding domain - - 613 895 1.4E-92
SUPERFAMILY SSF101790 Aminomethyltransferase beta-barrel domain IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal 906 1003 1.16E-17
NCBIfam TIGR01372 JCVI: sarcosine oxidase subunit alpha family protein IPR006277 Sarcosine oxidase, alpha subunit 2 1004 0.0
Gene3D G3DSA:3.10.20.440 - IPR042204 2Fe-2S iron-sulfur cluster binding domain, N-terminal 10 104 6.6E-21
Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain IPR013977 Glycine cleavage T-protein, C-terminal barrel domain 910 996 1.5E-19
PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature - - 284 292 1.5E-9

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.