Pseudomonas aeruginosa PAO1, PA0401

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0401
Name
Synonym: pyrC'
Synonym: pyrX
Replicon chromosome
Genomic location 443419 - 444690 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_249092.1
GI 15595598
Affymetrix PA0401_at
Entrez 878275
GenBank AAG03790.1
INSDC AAG03790.1
NCBI Locus Tag PA0401
protein_id(GenBank) gb|AAG03790.1|AE004477_7|gnl|PseudoCAP|PA0401
TIGR NTL03PA00402
UniParc UPI0000132E1D
UniProtKB Acc Q51551
UniProtKB ID PYRX_PSEAE
UniRef100 UniRef100_Q51551
UniRef50 UniRef50_Q51551
UniRef90 UniRef90_Q51551

Product

Feature Type CDS
Coding Frame 1
Product Name
noncatalytic dihydroorotase-like protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -8.26
Kyte-Doolittle Hydrophobicity Value 0.103
Molecular Weight (kDa) 44.1
Isoelectric Point (pI) 5.75

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 583 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000392 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0401

References

Aspartate transcarbamoylase genes of Pseudomonas putida: requirement for an inactive dihydroorotase for assembly into the dodecameric holoenzyme.
Schurr MJ, Vickrey JF, Kumar AP, Campbell AL, Cunin R, Benjamin RC, Shanley MS, O'Donovan GA
J. Bacteriol. 1995 Apr;177(7):1751-9
PubMed ID: 7896697
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994