Pseudomonas aeruginosa PAO1, PA0668 (tyrZ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0668
Name
tyrZ
Synonym: tyrS
Replicon chromosome
Genomic location 720357 - 721556 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249359.1
GI 15595865
Affymetrix PA0668_tyrZ_at
Entrez 880817
GenBank AAG04057.1
INSDC AAG04057.1
NCBI Locus Tag PA0668
protein_id(GenBank) gb|AAG04057.1|AE004501_9|gnl|PseudoCAP|PA0668
TIGR NTL03PA00669
UniParc UPI00000C50F1
UniProtKB Acc Q9I5Q3
UniProtKB ID SYY2_PSEAE
UniRef100 UniRef100_Q9I5Q3
UniRef50 UniRef50_P41256
UniRef90 UniRef90_Q9I5Q3

Product

Feature Type CDS
Coding Frame 1
Product Name
tyrosyl-tRNA synthetase 2
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by MALDI-TOF/TOF (PMID:19333994).
Charge (pH 7) -5.54
Kyte-Doolittle Hydrophobicity Value -0.192
Molecular Weight (kDa) 44.1
Isoelectric Point (pI) 5.55

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 659 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000647 (551 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0668
Search term: tyrZ

References

A gene encoding a tyrosine tRNA synthetase is located near sacS in Bacillus subtilis.
Glaser P, Kunst F, Débarbouillé M, Vertès A, Danchin A, Dedonder R
DNA Seq. 1991 ;1(4):251-61
PubMed ID: 1806041
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994