Pseudomonas aeruginosa UCBPP-PA14, PA14_11560 (ispA)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_11560
Name	ispA
Replicon	chromosome
Genomic location	999811 - 1000698 (- strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14

Cross-References

RefSeq	YP_789076.1
GI	116052080
Entrez	4382714
INSDC	ABJ13316.1
NCBI Locus Tag	PA14_11560
UniParc	UPI0000396267
UniProtKB Acc	Q02SL0
UniProtKB ID	Q02SL0_PSEAB
UniRef100	UniRef100_W0YWB7
UniRef50	UniRef50_A0A011QRS6
UniRef90	UniRef90_Q9HWY4

Product

Feature Type	CDS
Coding Frame	1
Product Name	geranyltranstransferase
Synonyms
Evidence for Translation
Charge (pH 7)	-8.43
Kyte-Doolittle Hydrophobicity Value	-0.037
Molecular Weight (kDa)	31.4
Isoelectric Point (pI)	5.06

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
3ZCD	TRANSFERASE	11/19/12	Native structure of Farnesyl Pyrophosphate Synthase from Pseudomonas aeruginosa PA01.	PSEUDOMONAS AERUGINOSA PAO1	1.55	X-RAY DIFFRACTION	99.7
4UMJ	TRANSFERASE	05/18/14	Native structure of Farnesyl Pyrophosphate Synthase from Pseudomonas aeruginosa PA01, with bound ibandronic acid molecules.	PSEUDOMONAS AERUGINOSA	1.85	X-RAY DIFFRACTION	99.7
3ZL6	TRANSFERASE	01/28/13	Native structure of Farnesyl Pyrophosphate Synthase from Pseudomonas aeruginosa PAO1, with bound fragment KM10833.	PSEUDOMONAS AERUGINOSA PAO1	1.85	X-RAY DIFFRACTION	99.7
3ZMC	TRANSFERASE	02/07/13	Native structure of Farnesyl Pyrophosphate Synthase from Pseudomonas aeruginosa PA01, with bound substrate molecule Geranyl pyrophosphate.	PSEUDOMONAS AERUGINOSA PAO1	1.87	X-RAY DIFFRACTION	99.7
3ZMB	TRANSFERASE	02/07/13	Native structure of Farnesyl Pyrophosphate Synthase from Pseudomonas aeruginosa PA01, with bound fragment SPB02696.	PSEUDOMONAS AERUGINOSA PAO1	1.9	X-RAY DIFFRACTION	99.7
3ZOU	TRANSFERASE	02/25/13	Native structure of Farnesyl Pyrophosphate Synthase from Pseudomonas aeruginosa PA01, with bound fragment SPB02696, and substrate geranyl pyrophosphate.	PSEUDOMONAS AERUGINOSA PAO1	1.55	X-RAY DIFFRACTION	99.7

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 656 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001641 (538 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_11560 Search term: ispA Search term: geranyltranstransferase

Human Homologs

References