Pseudomonas aeruginosa UCBPP-PA14, PA14_57390 (murF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
GCF_000014625.1|latest
Locus Tag
PA14_57390
Name
murF
Replicon chromosome
Genomic location 5113330 - 5114706 (- strand)

Cross-References

RefSeq YP_792762.1
GI 116052450
Entrez 4382520
INSDC ABJ13686.1
NCBI Locus Tag PA14_57390
UniParc UPI0000E44BDC
UniProtKB Acc Q02H24
UniProtKB ID Q02H24_PSEAB
UniRef100 UniRef100_Q02H24
UniRef50 UniRef50_Q87WY1
UniRef90 UniRef90_Q02H24

Product

Feature Type CDS
Coding Frame 1
Product Name
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate--D-alanyl-D-alanine ligase
Synonyms
Evidence for Translation
Charge (pH 7) -2.64
Kyte-Doolittle Hydrophobicity Value 0.156
Molecular Weight (kDa) 47.4
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4CVK LIGASE 03/28/14 PaMurF in complex with UDP-MurNAc-tripeptide (mDAP) PSEUDOMONAS AERUGINOSA PAO1 1.92 X-RAY DIFFRACTION 99.3
4CVM LIGASE 03/28/14 PaMurF in complex with AMP-PNP and UDP-MurNAc-tripeptide (mDAP) PSEUDOMONAS AERUGINOSA PAO1 2.06 X-RAY DIFFRACTION 99.3
4CVL LIGASE 03/28/14 PaMurF in complex with AMP-PNP PSEUDOMONAS AERUGINOSA PAO1 2.98 X-RAY DIFFRACTION 99.3

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 577 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004006 (551 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_57390
Search term: murF

References

No references are associated with this feature.