Pseudomonas aeruginosa PAO1, PA4772

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4772
Name
Replicon chromosome
Genomic location 5358442 - 5361258 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253460.1
GI 15599966
Affymetrix PA4772_at
Entrez 881816
GenBank AAG08158.1
INSDC AAG08158.1
NCBI Locus Tag PA4772
protein_id(GenBank) gb|AAG08158.1|AE004890_11|gnl|PseudoCAP|PA4772
TIGR NTL03PA04773
UniParc UPI00000C5DF9
UniProtKB Acc Q9HV36
UniProtKB ID Q9HV36_PSEAE
UniRef100 UniRef100_U8MW13
UniRef50 UniRef50_A6VRD5
UniRef90 UniRef90_A6VCM9

Product

Feature Type CDS
Coding Frame 1
Product Name
probable ferredoxin
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.62
Kyte-Doolittle Hydrophobicity Value -0.143
Molecular Weight (kDa) 102.6
Isoelectric Point (pI) 6.62

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 538 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004415 (500 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4772

Human Homologs

Ensembl 110, assembly GRCh38.p14
lactate dehydrogenase D [Source:HGNC Symbol;Acc:HGNC:19708]
E-value: 4.9e-24
Percent Identity: 26.0

References

The Archaeoglobus fulgidus D-lactate dehydrogenase is a Zn(2+) flavoprotein.
Reed DW, Hartzell PL
J Bacteriol 1999 Dec;181(24):7580-7
PubMed ID: 10601217
Carbon catabolite repression in Kluyveromyces lactis: isolation and characterization of the KIDLD gene encoding the mitochondrial enzyme D-lactate ferricytochrome c oxidoreductase.
Lodi T, O'Connor D, Goffrini P, Ferrero I
Mol Gen Genet 1994 Sep 28;244(6):622-9
PubMed ID: 7969031