Pseudomonas aeruginosa PAO1, PA0770 (rnc)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0770
Name
rnc
Replicon chromosome
Genomic location 838725 - 839414 (+ strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249461.1
GI 15595967
Affymetrix PA0770_rnc_at
DNASU PaCD00006353
Entrez 882139
GenBank AAG04159.1
INSDC AAG04159.1
NCBI Locus Tag PA0770
protein_id(GenBank) gb|AAG04159.1|AE004512_2|gnl|PseudoCAP|PA0770
TIGR NTL03PA00771
UniParc UPI000013435B
UniProtKB Acc Q9XCX9
UniProtKB ID RNC_PSEAE
UniRef100 UniRef100_B7UYX2
UniRef50 UniRef50_B7UYX2
UniRef90 UniRef90_B7UYX2

Product

Feature Type CDS
Coding Frame 1
Product Name
ribonuclease III
Product Name Confidence: Class 2
Synonyms RNAse III
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.40
Kyte-Doolittle Hydrophobicity Value -0.252
Molecular Weight (kDa) 25.5
Isoelectric Point (pI) 6.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 589 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000744 (552 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0770
Search term: rnc
Search term: ribonuclease III

Human Homologs

Ensembl 94, assembly GRCh38.p12
dicer 1, ribonuclease III [Source:HGNC Symbol;Acc:HGNC:17098]
E-value: 2.3e-13
Percent Identity: 27.4

References

DNA sequencing of the Escherichia coli ribonuclease III gene and its mutations.
Nashimoto H, Uchida H
Mol. Gen. Genet. 1985 ;201(1):25-9
PubMed ID: 3903434
A GTP-binding protein of Escherichia coli has homology to yeast RAS proteins.
Ahnn J, March PE, Takiff HE, Inouye M
Proc. Natl. Acad. Sci. U.S.A. 1986 Dec;83(23):8849-53
PubMed ID: 3097637
Expression and regulation of the rnc and pdxJ operons of Escherichia coli.
Matsunaga J, Dyer M, Simons EL, Simons RW
Mol. Microbiol. 1996 Dec;22(5):977-89
PubMed ID: 8971718