Pseudomonas aeruginosa PAO1, PA0649 (trpG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0649
Name
trpG
Synonym: pabA
Replicon chromosome
Genomic location 703477 - 704082 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249340.1
GI 15595846
Affymetrix PA0649_trpG_at
DNASU PaCD00006292
Entrez 878400
GenBank AAG04038.1
INSDC AAG04038.1
NCBI Locus Tag PA0649
protein_id(GenBank) gb|AAG04038.1|AE004500_4|gnl|PseudoCAP|PA0649
TIGR NTL03PA00650
UniParc UPI000013762A
UniProtKB Acc P20576
UniProtKB ID TRPG_PSEAE
UniRef100 UniRef100_P20576
UniRef50 UniRef50_P00903
UniRef90 UniRef90_P20576

Product

Feature Type CDS
Coding Frame 1
Product Name
anthranilate synthase component II
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.93
Kyte-Doolittle Hydrophobicity Value -0.087
Molecular Weight (kDa) 22.0
Isoelectric Point (pI) 6.02

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 648 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000629 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0649
Search term: trpG

References

DNA sequences and characterization of four early genes of the tryptophan pathway in Pseudomonas aeruginosa.
Essar DW, Eberly L, Han CY, Crawford IP
J Bacteriol 1990 Feb;172(2):853-66
PubMed ID: 2105306
Identification and characterization of genes for a second anthranilate synthase in Pseudomonas aeruginosa: interchangeability of the two anthranilate synthases and evolutionary implications.
Essar DW, Eberly L, Hadero A, Crawford IP
J Bacteriol 1990 Feb;172(2):884-900
PubMed ID: 2153661