Pseudomonas aeruginosa PAO1, PA3705 (wspD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3705
Name
wspD
Replicon chromosome
Genomic location 4148249 - 4148938 (- strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252394.1
GI 15598900
Affymetrix PA3705_at
Entrez 880395
GenBank AAG07092.1
INSDC AAG07092.1
NCBI Locus Tag PA3705
protein_id(GenBank) gb|AAG07092.1|AE004789_12|gnl|PseudoCAP|PA3705
TIGR NTL03PA03705
UniParc UPI00000C5ACC
UniProtKB Acc Q9HXT6
UniProtKB ID Q9HXT6_PSEAE
UniRef100 UniRef100_Q9HXT6
UniRef50 UniRef50_Q9HXT6
UniRef90 UniRef90_Q9HXT6

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.23
Kyte-Doolittle Hydrophobicity Value -0.041
Molecular Weight (kDa) 24.9
Isoelectric Point (pI) 5.31

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 45 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001974 (494 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3705
Search term: wspD

Human Homologs

References

Autolysis and autoaggregation in Pseudomonas aeruginosa colony morphology mutants.
D'Argenio DA, Calfee MW, Rainey PB, Pesci EC
J Bacteriol 2002 Dec;184(23):6481-9
PubMed ID: 12426335
"Frizzy" aggregation genes of the gliding bacterium Myxococcus xanthus show sequence similarities to the chemotaxis genes of enteric bacteria.
McBride MJ, Weinberg RA, Zusman DR
Proc Natl Acad Sci U S A 1989 Jan;86(2):424-8
PubMed ID: 2492105