Pseudomonas aeruginosa PA7, PSPA7_0457 (coaD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008771 [citrate (pro-3S)-lyase] ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00764
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004595 pantetheine-phosphate adenylyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd02163
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0015937 coenzyme A biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd02163
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009058 biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00125
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00125
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Central intermediary metabolism Other PA7 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pap01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap00770 Pantothenate and CoA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc coenzyme A biosynthesis II (eukaryotic) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature IPR001980 Phosphopantetheine adenylyltransferase 44 65 4.2E-50
NCBIfam TIGR00125 JCVI: cytidyltransferase-like domain IPR004821 Cytidyltransferase-like domain 27 87 1.9E-19
PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature IPR001980 Phosphopantetheine adenylyltransferase 73 97 4.2E-50
PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature IPR001980 Phosphopantetheine adenylyltransferase 26 44 4.2E-50
Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. IPR001980 Phosphopantetheine adenylyltransferase 26 182 36.503994
SUPERFAMILY SSF52374 Nucleotidylyl transferase - - 25 180 7.24E-47
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 20 183 4.7E-62
CDD cd02163 PPAT IPR001980 Phosphopantetheine adenylyltransferase 27 179 4.89004E-100
NCBIfam TIGR01510 JCVI: pantetheine-phosphate adenylyltransferase IPR001980 Phosphopantetheine adenylyltransferase 28 180 6.1E-59
Pfam PF01467 Cytidylyltransferase-like IPR004821 Cytidyltransferase-like domain 29 157 1.3E-23
PANTHER PTHR21342 PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE - - 26 182 4.6E-45
PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature IPR001980 Phosphopantetheine adenylyltransferase 136 158 4.2E-50
SMART SM00764 citrate_ly_lig5 IPR013166 Citrate lyase ligase, C-terminal 36 177 0.0096
PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature IPR001980 Phosphopantetheine adenylyltransferase 109 125 4.2E-50

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.